Objective To investigate the control effect of different intervention measures on the density of Aedes albopictus in residential areas,and to provide a reference for usual control of Ae.albopictus. Methods From April to December 2019,a residential area in Guangzhou,China,was selected as the test site,which consisted of four relatively independent and homogeneous residential communities.The four communities were randomly set as control group (A),artificial breeding ground treatment group (B),group treated by Bacillus thuringiensis with mist spraying at breeding sites (C),and group treated by ultra-low volume spraying of pyrethroid insecticides to kill adult mosquitoes (D).Only mosquito monitoring were performed in the control group.Since April 11,the container index (CI) method and the mosq-ovitrap method were used to monitor the density of Ae.albopictus once every two weeks.The first treatment was conducted on May 23,and then different treatment methods were used every two weeks.The area of each treatment,the number of persons dispatched,the time spent on treatment,and the costs of insecticides were record everytime.CI and mosq-ovitrap index (MOI) were calculated,and an analysis of variance was used to compare the control effect of different intervention measures. Results Before treatment,there were no statistically significant differences between the four groups in CI ( F=0.114, P=0.948) and MOI ( F=0.005, P=0.999).After the first treatment for 14 days,there were statistically significant differences between the four groups in CI ( F=602.371, P<0.001) and MOI ( F=57.619, P=0.001).After treatment for 14 days,CI of the B group decreased rapidly from 94.29% to 3.70% and then maintained at a relatively low level (CI ≤ 3.70%),and in the D group,MOI decreased from high risk (23.00) to moderate risk (16.00).The cost of renting equipment for one treatment in the B,C,and D groups was 0.91,2.80,and 0.93 yuan/hm ²,respectively.There was a difference in the economic cost required by the three intervention measures to reduce CI to low risk,with the lowest cost of 0.91 yuan/hm ² for the B group,and there was also a difference in the economic cost required to reduce MOI to low risk,with the lowest cost of 1.86 yuan/hm ² for the D group. Conclusion B group supplemented by C group can be used as the main measure for usual control of Ae.albopictus density in residential areas,so as to control the density of Ae.albopictus in an economic,environmentally friendly,and efficient manner.